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 Technology Information 
TitleMethods for Reducing Seizure-induced Neuronal Damage
Case Number1394
AbstractName of the inventor: Shi Du Yan, Guy McKhann, David M. Stern

A method for treating a subject either during or soon after a seizure, in order to reduce the extent of the resulting neuronal damage is described.

A method for inhibiting neuronal damage comprises administering a prophylactically effective amount of an inhibitor/receptor for advanced glycation end products (RAGE) which would otherwise result from a seizure in the event the subject were to suffer a seizure.

The method is useful in the treatment/inhibition of human seizure disorders.
TaxonomyTherapeutic/Healthcare
Sm Molecule/Therapeutic
Keywordsneuron, seizure, RAGE, Neuroscience, biopharma
 Licensing Contact 
The responsible technology licensing officer is Jerry Kokoshka but for more information on this technology, please contact stvinfo@columbia.edu .
 Web Links 
Name Description Open Link
Patent number: WO2005042782 Click Here
USPTO US20080260717A1 Click Here

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